Nrf2 overexpression increases the resistance of acute myeloid leukemia to cytarabine by inhibiting replication factor C4

Drug resistance is a key factor in the treatment failure of acute myeloid leukemia (AML). Nuclear factor E2-related factor 2 (Nrf2) plays a crucial role in tumor chemotherapy resistance. However, the potential mechanism of Nrf2 regulating DNA mismatch repair (MMR) pathway to mediate gene-instability...

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Detalles Bibliográficos
Autores principales: Hu, Tianzhen, Pan, Chengyun, Zhang, Tianzhuo, Ni, Ming, Wang, Weili, Zhang, Siyu, Chen, Ying, Wang, Jishi, Fang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663296/
https://www.ncbi.nlm.nih.gov/pubmed/35840666
http://dx.doi.org/10.1038/s41417-022-00501-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663296/
https://www.ncbi.nlm.nih.gov/pubmed/35840666
http://dx.doi.org/10.1038/s41417-022-00501-1

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