Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism

TAZ, one of the key effectors in the Hippo pathway, is often dysregulated in breast cancer, leading to cancer stemness, survival, and metastasis. However, the mechanistic bases of these tumor outcomes are incompletely understood and even less is known about the potential role played by the non-malig...

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Detalles Bibliográficos
Autores principales: Shen, He, Zhang, Yuwen, Kramer, Elliot D., Katsuta, Eriko, Wan, Yin, Chen, Yanmin, Wang, Jianmin, Zhang, Yali, Matsuzaki, Junko, Frangou, Costa, Abrams, Scott I., Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663307/
https://www.ncbi.nlm.nih.gov/pubmed/35840667
http://dx.doi.org/10.1038/s41417-022-00502-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663307/
https://www.ncbi.nlm.nih.gov/pubmed/35840667
http://dx.doi.org/10.1038/s41417-022-00502-0

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