Structural and mutational studies suggest key residues to determine whether stomatin SPFH domains form dimers or trimers

Stomatin is a major integral membrane protein in human erythrocytes. In a form of hemolytic anemia known as hereditary stomatocytosis, stomatin is deficient in the erythrocyte membrane due to mis-trafficking. It is a member of stomatin, prohibitin, flotillin, and HflK/C (SPFH) domain proteins, and S...

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Detalles Bibliográficos
Autores principales: Komatsu, Tomoya, Matsui, Ikuo, Yokoyama, Hideshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663324/
https://www.ncbi.nlm.nih.gov/pubmed/36386441
http://dx.doi.org/10.1016/j.bbrep.2022.101384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663324/
https://www.ncbi.nlm.nih.gov/pubmed/36386441
http://dx.doi.org/10.1016/j.bbrep.2022.101384

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