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Structural and mutational studies suggest key residues to determine whether stomatin SPFH domains form dimers or trimers
Stomatin is a major integral membrane protein in human erythrocytes. In a form of hemolytic anemia known as hereditary stomatocytosis, stomatin is deficient in the erythrocyte membrane due to mis-trafficking. It is a member of stomatin, prohibitin, flotillin, and HflK/C (SPFH) domain proteins, and S...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663324/ https://www.ncbi.nlm.nih.gov/pubmed/36386441 http://dx.doi.org/10.1016/j.bbrep.2022.101384 |