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Risk of gastric and oesophageal adenocarcinoma following discontinuation of long-term proton-pump inhibitor therapy

BACKGROUND: There is uncertainty whether long-term use of proton-pump inhibitors can cause gastric adenocarcinoma (GAC) and oesophageal adenocarcinoma (OAC). This study aimed to determine how discontinuation of long-term PPI therapy influences the risk of GAC and OAC. METHODS: This population-based...

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Detalles Bibliográficos
Autores principales: Holmberg, Dag, Mattsson, Fredrik, Xie, Shaohua, Ness-Jensen, Eivind, El-Serag, Hashem, Lagergren, Jesper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663349/
https://www.ncbi.nlm.nih.gov/pubmed/36258093
http://dx.doi.org/10.1007/s00535-022-01930-3