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Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling

Neonatal necrotizing enterocolitis (NEC) is an inflammatory disease that occurs in premature infants and has a high mortality rate; however, the mechanisms behind this disease remain unclear. The TLR4 signaling pathway in intestinal epithelial cells, mediated by TLR4, is important for the activation...

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Detalles Bibliográficos
Autores principales: Huang, Dabin, Wang, Ping, Chen, Juncao, Li, Yanbin, Zhu, Mingwei, Tang, Yaping, Zhou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663461/
https://www.ncbi.nlm.nih.gov/pubmed/36389716
http://dx.doi.org/10.3389/fimmu.2022.995791