An extracellular receptor tyrosine kinase motif orchestrating intracellular STAT activation

The ErbB4 receptor isoforms JM-a and JM-b differ within their extracellular juxtamembrane (eJM) domains. Here, ErbB4 isoforms are used as a model to address the effect of structural variation in the eJM domain of receptor tyrosine kinases (RTK) on downstream signaling. A specific JM-a-like sequence...

Descripción completa

Detalles Bibliográficos
Autores principales: Vaparanta, Katri, Jokilammi, Anne, Tamirat, Mahlet, Merilahti, Johannes A. M., Salokas, Kari, Varjosalo, Markku, Ivaska, Johanna, Johnson, Mark S., Elenius, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663514/
https://www.ncbi.nlm.nih.gov/pubmed/36376313
http://dx.doi.org/10.1038/s41467-022-34539-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663514/
https://www.ncbi.nlm.nih.gov/pubmed/36376313
http://dx.doi.org/10.1038/s41467-022-34539-4

Ejemplares similares