The brain-specific splice variant of the CDC42 GTPase works together with the kinase ACK to downregulate the EGF receptor in promoting neurogenesis

The small GTPase CDC42 plays essential roles in neurogenesis and brain development. Previously, we showed that a CDC42 splice variant that has a ubiquitous tissue distribution specifically stimulates the formation of neural progenitor cells, whereas a brain-specific CDC42 variant, CDC42b, is essenti...

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Detalles Bibliográficos
Autores principales: Endo, Makoto, Cerione, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663532/
https://www.ncbi.nlm.nih.gov/pubmed/36206843
http://dx.doi.org/10.1016/j.jbc.2022.102564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663532/
https://www.ncbi.nlm.nih.gov/pubmed/36206843
http://dx.doi.org/10.1016/j.jbc.2022.102564

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