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Hybrid nanoparticulate system of Fluvastatin loaded phospholipid, alpha lipoic acid and melittin for the management of colon cancer

As a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, Fluvastatin (FLV) is used for reducing low-density lipoprotein (LDL) cholesterol as well as to prevent cardiovascular problems. FLV showed cell line cytotoxicity and antitumor effect. Melittin (MEL) exhibits antineoplastic activity...

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Detalles Bibliográficos
Autores principales: Alfaleh, Mohamed A., Fahmy, Omar, Al-Rabia, Mohammed W., Abourehab, Mohammed A. S., Ahmed, Osama A. A., Fahmy, Usama A., H. Alsulimani, Helal, Badr-Eldin, Shaimaa M., Aldawsari, Hibah M., Aldhabi, Bander M., Alharbi, Awaad S., Alhakamy, Nabil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663543/
https://www.ncbi.nlm.nih.gov/pubmed/36376469
http://dx.doi.org/10.1038/s41598-022-24151-3