GALNT14-mediated O-glycosylation on PHB2 serine-161 enhances cell growth, migration and drug resistance by activating IGF1R cascade in hepatoma cells

The single nucleotide polymorphism (SNP) rs9679162 located on GALNT14 gene predicts therapeutic outcomes in patients with intermediate and advanced hepatocellular carcinoma (HCC), but the molecular mechanism remains unclear. Here, the associations between SNP genotypes, GALNT14 expression, and downs...

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Detalles Bibliográficos
Autores principales: Chu, Yu-De, Fan, Tan-Chi, Lai, Ming-Wei, Yeh, Chau-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663550/
https://www.ncbi.nlm.nih.gov/pubmed/36376274
http://dx.doi.org/10.1038/s41419-022-05419-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663550/
https://www.ncbi.nlm.nih.gov/pubmed/36376274
http://dx.doi.org/10.1038/s41419-022-05419-y

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