The 3D enhancer network of the developing T cell genome is shaped by SATB1

Mechanisms of tissue-specific gene expression regulation via 3D genome organization are poorly understood. Here we uncover the regulatory chromatin network of developing T cells and identify SATB1, a tissue-specific genome organizer, enriched at the anchors of promoter-enhancer loops. We have genera...

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Detalles Bibliográficos
Autores principales: Zelenka, Tomas, Klonizakis, Antonios, Tsoukatou, Despina, Papamatheakis, Dionysios-Alexandros, Franzenburg, Sören, Tzerpos, Petros, Tzonevrakis, Ioannis-Rafail, Papadogkonas, George, Kapsetaki, Manouela, Nikolaou, Christoforos, Plewczynski, Dariusz, Spilianakis, Charalampos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663569/
https://www.ncbi.nlm.nih.gov/pubmed/36376298
http://dx.doi.org/10.1038/s41467-022-34345-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663569/
https://www.ncbi.nlm.nih.gov/pubmed/36376298
http://dx.doi.org/10.1038/s41467-022-34345-y

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