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Inducer-free cellulase production system based on the constitutive expression of mutated XYR1 and ACE3 in the industrial fungus Trichoderma reesei

Trichoderma reesei is a widely used host for producing cellulase and hemicellulase cocktails for lignocellulosic biomass degradation. Here, we report a genetic modification strategy for industrial T. reesei that enables enzyme production using simple glucose without inducers, such as cellulose, lact...

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Detalles Bibliográficos
Autores principales: Arai, Toshiharu, Ichinose, Sakurako, Shibata, Nozomu, Kakeshita, Hiroshi, Kodama, Hiroshi, Igarashi, Kazuaki, Takimura, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663580/
https://www.ncbi.nlm.nih.gov/pubmed/36376415
http://dx.doi.org/10.1038/s41598-022-23815-4