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Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP

The emergence of methicillin-resistant Staphylococcus aureus isolates highlights the urgent need to develop more antibiotics. ClpP is a highly conserved protease regulated by ATPases in bacteria and in mitochondria. Aberrant activation of  bacterial ClpP is an alternative method of discovering antib...

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Detalles Bibliográficos
Autores principales: Wei, Bingyan, Zhang, Tao, Wang, Pengyu, Pan, Yihui, Li, Jiahui, Chen, Weizhong, Zhang, Min, Ji, Quanjiang, Wu, Wenjuan, Lan, Lefu, Gan, Jianhua, Yang, Cai-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663597/
https://www.ncbi.nlm.nih.gov/pubmed/36376309
http://dx.doi.org/10.1038/s41467-022-34753-0