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Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP
The emergence of methicillin-resistant Staphylococcus aureus isolates highlights the urgent need to develop more antibiotics. ClpP is a highly conserved protease regulated by ATPases in bacteria and in mitochondria. Aberrant activation of bacterial ClpP is an alternative method of discovering antib...
Autores principales: | Wei, Bingyan, Zhang, Tao, Wang, Pengyu, Pan, Yihui, Li, Jiahui, Chen, Weizhong, Zhang, Min, Ji, Quanjiang, Wu, Wenjuan, Lan, Lefu, Gan, Jianhua, Yang, Cai-Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663597/ https://www.ncbi.nlm.nih.gov/pubmed/36376309 http://dx.doi.org/10.1038/s41467-022-34753-0 |
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