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5-HT(1B) receptor agonist enhances breakpoint for cocaine on a progressive ratio (PR) schedule during maintenance of self-administration in female rats but reduces breakpoint for sucrose

Background: Previous research showed that the 5-HT(1B) receptor agonist CP94253 enhanced cocaine reinforcement rate during maintenance of daily self-administration (SA), but inhibited reinforcement rate after 21 days of abstinence in male rats. Here we examined whether female rats show similar effec...

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Detalles Bibliográficos
Autores principales: Scott, Samantha N., Ruscitti, Brielle A., Garcia, Raul, Nguyen, Toan T., Blattner, Kevin M., Blass, Benjamin E., Neisewander, Janet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663667/
https://www.ncbi.nlm.nih.gov/pubmed/36386780
http://dx.doi.org/10.3389/fnbeh.2022.1020146