Proline, hydroxyproline, and pyrrolidone carboxylic acid derivatives as highly efficient but reversible transdermal permeation enhancers

Overcoming the skin barrier properties efficiently, temporarily, and safely for successful transdermal drug delivery remains a challenge. We synthesized three series of potential skin permeation enhancers derived from natural amino acid derivatives proline, 4-hydroxyproline, and pyrrolidone carboxyl...

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Detalles Bibliográficos
Autores principales: Kopečná, Monika, Macháček, Miloslav, Roh, Jaroslav, Vávrová, Kateřina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663686/
https://www.ncbi.nlm.nih.gov/pubmed/36376455
http://dx.doi.org/10.1038/s41598-022-24108-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663686/
https://www.ncbi.nlm.nih.gov/pubmed/36376455
http://dx.doi.org/10.1038/s41598-022-24108-6

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