A new negative feedback mechanism for MAPK pathway inactivation through Srk1 MAPKAP kinase

The fission yeast mitogen-activated kinase (MAPK) Sty1 is essential for cell survival in response to different environmental insults. In unstimulated cells, Sty1 forms an inactive ternary cytoplasmatic complex with the MAPKK Wis1 and the MAPKAP kinase Srk1. Wis1 phosphorylates and activates Sty1, in...

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Detalles Bibliográficos
Autores principales: Marquina, Maribel, Lambea, Eva, Carmona, Mercé, Sánchez-Marinas, Marta, López-Aviles, Sandra, Ayte, José, Hidalgo, Elena, Aligue, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663701/
https://www.ncbi.nlm.nih.gov/pubmed/36376357
http://dx.doi.org/10.1038/s41598-022-23970-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663701/
https://www.ncbi.nlm.nih.gov/pubmed/36376357
http://dx.doi.org/10.1038/s41598-022-23970-8

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