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Tfh cells and the germinal center are required for memory B cell formation & humoral immunity after ChAdOx1 nCoV-19 vaccination

Emergence from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been facilitated by the rollout of effective vaccines. Successful vaccines generate high-affinity plasma blasts and long-lived protective memory B cells. Here, we show a requirement for T follicular helper (...

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Detalles Bibliográficos
Autores principales: Foster, William S., Lee, Jia Le, Thakur, Nazia, Newman, Joseph, Spencer, Alexandra J., Davies, Sophie, Woods, Danielle, Godfrey, Leila, Hay, Iain M., Innocentin, Silvia, Yam-Puc, Juan Carlos, Horner, Emily C., Sharpe, Hayley J., Thaventhiran, James E., Bailey, Dalan, Lambe, Teresa, Linterman, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663747/
https://www.ncbi.nlm.nih.gov/pubmed/36455555
http://dx.doi.org/10.1016/j.xcrm.2022.100845