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Tfh cells and the germinal center are required for memory B cell formation & humoral immunity after ChAdOx1 nCoV-19 vaccination
Emergence from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been facilitated by the rollout of effective vaccines. Successful vaccines generate high-affinity plasma blasts and long-lived protective memory B cells. Here, we show a requirement for T follicular helper (...
Autores principales: | Foster, William S., Lee, Jia Le, Thakur, Nazia, Newman, Joseph, Spencer, Alexandra J., Davies, Sophie, Woods, Danielle, Godfrey, Leila, Hay, Iain M., Innocentin, Silvia, Yam-Puc, Juan Carlos, Horner, Emily C., Sharpe, Hayley J., Thaventhiran, James E., Bailey, Dalan, Lambe, Teresa, Linterman, Michelle A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663747/ https://www.ncbi.nlm.nih.gov/pubmed/36455555 http://dx.doi.org/10.1016/j.xcrm.2022.100845 |
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