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SFTPB (rs11130866) and NR3C1 (rs41423247) gene variants as potential clinical biomarkers for personalized treatment strategy selection in patients with severe COVID-19 pneumonia

BACKGROUND: Exploring the pathogenetic mechanisms behind severe lung damage in COVID-19 is crucial. In this study, we decided to focus on two molecular markers that affect surfactant metabolism and lung development: the surfactant protein B (SFTPB) and the glucocorticoid receptor (NR3C1) genes. The...

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Detalles Bibliográficos
Autores principales:	Fishchuk, Liliia, Rossokha, Zoia, Pokhylko, Valeriy, Cherniavska, Yuliia, Popova, Olena, Vershyhora, Viktoriia, Kovtun, Serhii, Gorovenko, Nataliia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Respiratory Society. Published by Elsevier B.V. 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663752/ https://www.ncbi.nlm.nih.gov/pubmed/36460583 http://dx.doi.org/10.1016/j.resinv.2022.10.008

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