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Canine polarized macrophages express distinct functional and transcriptomic profiles

Macrophage differentiation and function in disease states is highly regulated by the local microenvironment. For example, macrophage exposure to IFN-γ (interferon gamma) initiates the development of inflammatory (M1) macrophages, which acquire anti-tumoral and antimicrobial activity, while exposure...

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Detalles Bibliográficos
Autores principales: Chow, Lyndah, Soontararak, Sirikul, Wheat, William, Ammons, Dylan, Dow, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663804/
https://www.ncbi.nlm.nih.gov/pubmed/36387411
http://dx.doi.org/10.3389/fvets.2022.988981