Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia

There is increasing genetic evidence for the role of microglia in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and motor neuron disease. Therefore, there is a need to generate authentic in vitro models to study human microglial physiology. Various methods have been developed using...

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Detalles Bibliográficos
Autores principales: Washer, Sam J., Perez-Alcantara, Marta, Chen, Yixi, Steer, Juliette, James, William S., Trynka, Gosia, Bassett, Andrew R., Cowley, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663826/
https://www.ncbi.nlm.nih.gov/pubmed/36376339
http://dx.doi.org/10.1038/s41598-022-23477-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663826/
https://www.ncbi.nlm.nih.gov/pubmed/36376339
http://dx.doi.org/10.1038/s41598-022-23477-2

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