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Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia
There is increasing genetic evidence for the role of microglia in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and motor neuron disease. Therefore, there is a need to generate authentic in vitro models to study human microglial physiology. Various methods have been developed using...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663826/ https://www.ncbi.nlm.nih.gov/pubmed/36376339 http://dx.doi.org/10.1038/s41598-022-23477-2 |