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Tumor suppressor DEAR1 regulates mammary epithelial cell fate and predicts early onset and metastasis in triple negative breast cancer

Triple negative breast cancer (TNBC) is a disease of poor prognosis, with the majority classified as the basal-like subtype associated with epithelial-mesenchymal transition and metastasis. Because basal breast cancers originate from proliferative luminal progenitor-like cells upon dysregulation of...

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Detalles Bibliográficos
Autores principales: Le, Uyen Q., Chen, Nanyue, Balasenthil, Seetharaman, Lurie, Eugene, Yang, Fei, Liu, Suyu, Rubin, Laura, Solis Soto, Luisa Maren, Raso, Maria Gabriela, Batra, Harsh, Sahin, Aysegul A., Wistuba, Ignacio I., Killary, Ann McNeill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663828/
https://www.ncbi.nlm.nih.gov/pubmed/36376460
http://dx.doi.org/10.1038/s41598-022-22417-4