IL-1β promotes IL-9-producing Th cell differentiation in IL-2-limiting conditions through the inhibition of BCL6

IL-9-producing CD4(+) T helper cells, termed Th9 cells, differentiate from naïve precursor cells in response to a combination of cytokine and cell surface receptor signals that are elevated in inflamed tissues. After differentiation, Th9 cells accumulate in these tissues where they exacerbate allerg...

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Detalles Bibliográficos
Autores principales: Canaria, D. Alejandro, Clare, Maia G., Yan, Bingyu, Campbell, Charlotte B., Ismaio, Zachariah A., Anderson, Nicole L., Park, Sungtae, Dent, Alexander L., Kazemian, Majid, Olson, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663844/
https://www.ncbi.nlm.nih.gov/pubmed/36389679
http://dx.doi.org/10.3389/fimmu.2022.1032618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663844/
https://www.ncbi.nlm.nih.gov/pubmed/36389679
http://dx.doi.org/10.3389/fimmu.2022.1032618

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