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Inhibitory Siglec-sialic acid interactions in balancing immunological activation and tolerance during viral infections

Siglecs are a family of emerging glyco-immune checkpoints. Inhibiting them can enhance the functions of several types of immune cells, whereas engaging them can reduce hyper-inflammation and hyper-activation of immune functions. Siglec-sialoglycan interactions play an important role in modulating im...

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Detalles Bibliográficos
Autores principales: Saini, Pratima, Adeniji, Opeyemi S., Abdel-Mohsen, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663867/
https://www.ncbi.nlm.nih.gov/pubmed/36371982
http://dx.doi.org/10.1016/j.ebiom.2022.104354