Cargando…
Inhibitory Siglec-sialic acid interactions in balancing immunological activation and tolerance during viral infections
Siglecs are a family of emerging glyco-immune checkpoints. Inhibiting them can enhance the functions of several types of immune cells, whereas engaging them can reduce hyper-inflammation and hyper-activation of immune functions. Siglec-sialoglycan interactions play an important role in modulating im...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663867/ https://www.ncbi.nlm.nih.gov/pubmed/36371982 http://dx.doi.org/10.1016/j.ebiom.2022.104354 |