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A one month high fat diet disrupts the gut microbiome and integrity of the colon inducing adiposity and behavioral despair in male Sprague Dawley rats

High-fat diet (HFD) is associated with gut microbiome dysfunction and mental disorders. However, the time-dependence as to when this occurs is unclear. We hypothesized that a short-term HFD causes colonic tissue integrity changes resulting in behavioral changes. Rats were fed HFD or low-fat diet (LF...

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Detalles Bibliográficos
Autores principales: Chompre, Gladys, Sambolin, Lubriel, Cruz, Myrella L., Sanchez, Rafael, Rodriguez, Yarelis, Rodríguez-Santiago, Ronald E., Yamamura, Yasuhiro, Appleyard, Caroline B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663868/
https://www.ncbi.nlm.nih.gov/pubmed/36387539
http://dx.doi.org/10.1016/j.heliyon.2022.e11194