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A one month high fat diet disrupts the gut microbiome and integrity of the colon inducing adiposity and behavioral despair in male Sprague Dawley rats
High-fat diet (HFD) is associated with gut microbiome dysfunction and mental disorders. However, the time-dependence as to when this occurs is unclear. We hypothesized that a short-term HFD causes colonic tissue integrity changes resulting in behavioral changes. Rats were fed HFD or low-fat diet (LF...
Autores principales: | Chompre, Gladys, Sambolin, Lubriel, Cruz, Myrella L., Sanchez, Rafael, Rodriguez, Yarelis, Rodríguez-Santiago, Ronald E., Yamamura, Yasuhiro, Appleyard, Caroline B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663868/ https://www.ncbi.nlm.nih.gov/pubmed/36387539 http://dx.doi.org/10.1016/j.heliyon.2022.e11194 |
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