Sensitization effect of kaempferol from persimmon leaves on HepG2 hepatoma cells with ABT-199 resistance and its molecular mechanisms

ABT-199 (venetoclax) is the first-in-class selective B-cell lymphoma 2 (BCL2) inhibitor, which is known to be ineffective towards liver cancer cells. Here, we investigated the efficacy and the underlying molecular processes of the sensitization effect of kaempferol isolated from persimmon leaves (KP...

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Detalles Bibliográficos
Autores principales: Chen, Li, Jiang, Xudong, Gao, Si, Liu, Xueping, Gao, Ying, Kow, Audrey Siew Foong, Tham, Chau Ling, Lee, Ming Tatt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663918/
https://www.ncbi.nlm.nih.gov/pubmed/36386146
http://dx.doi.org/10.3389/fphar.2022.1032069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663918/
https://www.ncbi.nlm.nih.gov/pubmed/36386146
http://dx.doi.org/10.3389/fphar.2022.1032069

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