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Sensitization effect of kaempferol from persimmon leaves on HepG2 hepatoma cells with ABT-199 resistance and its molecular mechanisms
ABT-199 (venetoclax) is the first-in-class selective B-cell lymphoma 2 (BCL2) inhibitor, which is known to be ineffective towards liver cancer cells. Here, we investigated the efficacy and the underlying molecular processes of the sensitization effect of kaempferol isolated from persimmon leaves (KP...
Autores principales: | Chen, Li, Jiang, Xudong, Gao, Si, Liu, Xueping, Gao, Ying, Kow, Audrey Siew Foong, Tham, Chau Ling, Lee, Ming Tatt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663918/ https://www.ncbi.nlm.nih.gov/pubmed/36386146 http://dx.doi.org/10.3389/fphar.2022.1032069 |
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