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Do cross-food allergies to propofol exist?
BACKGROUND: Propofol is a short and rapidly acting intravenous anesthetic extensively used for the induction and maintenance of general anesthesia. It is a lipid emulsion that contains soybean oil, purified egg phosphatide, and egg lecithin. Therefore, the package leaflet indicates that its administ...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Anesthesiologists
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663949/ https://www.ncbi.nlm.nih.gov/pubmed/36317430 http://dx.doi.org/10.17085/apm.22195 |
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author | Ramírez, Carles Espinós Domingo, Marta Viñas Font, Anna Peig Esteller, Paula Gil Marchuet, Maria José Castillo Foix, Maria Pilar Saura Sanchez, Juan Carlos Martín García, Maria Martinez |
author_facet | Ramírez, Carles Espinós Domingo, Marta Viñas Font, Anna Peig Esteller, Paula Gil Marchuet, Maria José Castillo Foix, Maria Pilar Saura Sanchez, Juan Carlos Martín García, Maria Martinez |
author_sort | Ramírez, Carles Espinós |
collection | PubMed |
description | BACKGROUND: Propofol is a short and rapidly acting intravenous anesthetic extensively used for the induction and maintenance of general anesthesia. It is a lipid emulsion that contains soybean oil, purified egg phosphatide, and egg lecithin. Therefore, the package leaflet indicates that its administration is contraindicated in patients allergic to soy, eggs, or peanuts. Our study aimed to determine whether patients with proven food allergies are allergic to propofol. METHODS: Patients of all ages allergic to soy, eggs, or peanuts who agreed to undergo skin testing for propofol allergies were included. The subjects first underwent a skin test to confirm food allergies. If candidates were negative, they were excluded. If the result was positive, a propofol skin test was performed. RESULTS: Sixty-four patients with confirmed food allergies underwent a propofol skin test. Only one was positive in the propofol skin test (1.6%). The patient was allergic to peanuts and soybeans. These results reinforce the idea that there is no justification for avoiding propofol use in these subjects. CONCLUSIONS: Propofol can be safely administered to patients allergic to soy, eggs, or peanuts. We recommend caution in patients with a history of anaphylaxis after ingestion of the above-mentioned foods. |
format | Online Article Text |
id | pubmed-9663949 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Korean Society of Anesthesiologists |
record_format | MEDLINE/PubMed |
spelling | pubmed-96639492022-11-28 Do cross-food allergies to propofol exist? Ramírez, Carles Espinós Domingo, Marta Viñas Font, Anna Peig Esteller, Paula Gil Marchuet, Maria José Castillo Foix, Maria Pilar Saura Sanchez, Juan Carlos Martín García, Maria Martinez Anesth Pain Med (Seoul) Anesthetic Pharmacology BACKGROUND: Propofol is a short and rapidly acting intravenous anesthetic extensively used for the induction and maintenance of general anesthesia. It is a lipid emulsion that contains soybean oil, purified egg phosphatide, and egg lecithin. Therefore, the package leaflet indicates that its administration is contraindicated in patients allergic to soy, eggs, or peanuts. Our study aimed to determine whether patients with proven food allergies are allergic to propofol. METHODS: Patients of all ages allergic to soy, eggs, or peanuts who agreed to undergo skin testing for propofol allergies were included. The subjects first underwent a skin test to confirm food allergies. If candidates were negative, they were excluded. If the result was positive, a propofol skin test was performed. RESULTS: Sixty-four patients with confirmed food allergies underwent a propofol skin test. Only one was positive in the propofol skin test (1.6%). The patient was allergic to peanuts and soybeans. These results reinforce the idea that there is no justification for avoiding propofol use in these subjects. CONCLUSIONS: Propofol can be safely administered to patients allergic to soy, eggs, or peanuts. We recommend caution in patients with a history of anaphylaxis after ingestion of the above-mentioned foods. Korean Society of Anesthesiologists 2022-10-31 2022-10-20 /pmc/articles/PMC9663949/ /pubmed/36317430 http://dx.doi.org/10.17085/apm.22195 Text en Copyright © the Korean Society of Anesthesiologists, 2022 https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Anesthetic Pharmacology Ramírez, Carles Espinós Domingo, Marta Viñas Font, Anna Peig Esteller, Paula Gil Marchuet, Maria José Castillo Foix, Maria Pilar Saura Sanchez, Juan Carlos Martín García, Maria Martinez Do cross-food allergies to propofol exist? |
title | Do cross-food allergies to propofol exist? |
title_full | Do cross-food allergies to propofol exist? |
title_fullStr | Do cross-food allergies to propofol exist? |
title_full_unstemmed | Do cross-food allergies to propofol exist? |
title_short | Do cross-food allergies to propofol exist? |
title_sort | do cross-food allergies to propofol exist? |
topic | Anesthetic Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663949/ https://www.ncbi.nlm.nih.gov/pubmed/36317430 http://dx.doi.org/10.17085/apm.22195 |
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