The Food and Drug Administration-approved antipsychotic drug trifluoperazine, a calmodulin antagonist, inhibits viral replication through PERK-eIF2α axis

Virus-related diseases are seriously threatening human health, but there are currently only 10 viruses with clinically approved antiviral drugs available. As non-cellular organisms, viruses parasitize in living cells and rely on the protein synthesis mechanism of the host cells. In this study, we fo...

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Detalles Bibliográficos
Autores principales: Mao, Yizhi, Wang, Ziyang, Yao, Chen, Zeng, Qi, Cheng, Wei, Zhang, Shimeng, Chen, Shuai, Sheng, Chunjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664084/
https://www.ncbi.nlm.nih.gov/pubmed/36386620
http://dx.doi.org/10.3389/fmicb.2022.979904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664084/
https://www.ncbi.nlm.nih.gov/pubmed/36386620
http://dx.doi.org/10.3389/fmicb.2022.979904

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