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The Food and Drug Administration-approved antipsychotic drug trifluoperazine, a calmodulin antagonist, inhibits viral replication through PERK-eIF2α axis
Virus-related diseases are seriously threatening human health, but there are currently only 10 viruses with clinically approved antiviral drugs available. As non-cellular organisms, viruses parasitize in living cells and rely on the protein synthesis mechanism of the host cells. In this study, we fo...
Autores principales: | Mao, Yizhi, Wang, Ziyang, Yao, Chen, Zeng, Qi, Cheng, Wei, Zhang, Shimeng, Chen, Shuai, Sheng, Chunjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664084/ https://www.ncbi.nlm.nih.gov/pubmed/36386620 http://dx.doi.org/10.3389/fmicb.2022.979904 |
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