FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM2

OBJECTIVE: Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented. Herein, we aimed to characterise the roles of macrophage FSTL1 in the development of liver fibrosis...

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Detalles Bibliográficos
Autores principales: Rao, Jianhua, Wang, Hao, Ni, Ming, Wang, Zeng, Wang, Ziyi, Wei, Song, Liu, Mu, Wang, Peng, Qiu, Jiannan, Zhang, Lei, Wu, Chen, Shen, Hongbing, Wang, Xuehao, Cheng, Feng, Lu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664121/
https://www.ncbi.nlm.nih.gov/pubmed/35140065
http://dx.doi.org/10.1136/gutjnl-2021-325150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664121/
https://www.ncbi.nlm.nih.gov/pubmed/35140065
http://dx.doi.org/10.1136/gutjnl-2021-325150

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