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PD-L1 blockade liberates intrinsic antitumourigenic properties of glycolytic macrophages in hepatocellular carcinoma

OBJECTIVE: Patients with increased PD-L1(+) host cells in tumours are more potent to benefit from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the underlying mechanism is still unclear. We aim to elucidate the nature, regulation and functional relevance of PD-L1(+) host ce...

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Detalles Bibliográficos
Autores principales: Lu, Li-Gong, Zhou, Zhi-Ling, Wang, Xu-Yan, Liu, Bo-Yuan, Lu, Jin-Ying, Liu, Shuai, Zhang, Guang-Bo, Zhan, Mei-Xiao, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664131/
https://www.ncbi.nlm.nih.gov/pubmed/35173040
http://dx.doi.org/10.1136/gutjnl-2021-326350