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PD-L1 blockade liberates intrinsic antitumourigenic properties of glycolytic macrophages in hepatocellular carcinoma
OBJECTIVE: Patients with increased PD-L1(+) host cells in tumours are more potent to benefit from antiprogrammed death-1/programmed death ligand-1 (PD-L1) treatment, but the underlying mechanism is still unclear. We aim to elucidate the nature, regulation and functional relevance of PD-L1(+) host ce...
Autores principales: | Lu, Li-Gong, Zhou, Zhi-Ling, Wang, Xu-Yan, Liu, Bo-Yuan, Lu, Jin-Ying, Liu, Shuai, Zhang, Guang-Bo, Zhan, Mei-Xiao, Chen, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664131/ https://www.ncbi.nlm.nih.gov/pubmed/35173040 http://dx.doi.org/10.1136/gutjnl-2021-326350 |
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