Neutralization of the adaptor protein PAG by monoclonal antibody limits murine tumor growth

The transmembrane adaptor phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (PAG) is phosphorylated in T cells downstream of PD-1 signaling and contributes to the resulting functional inhibition of multiple cellular processes. Furthermore, PAG expression is negatively correlat...

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Detalles Bibliográficos
Autores principales: Strazza, Marianne, Moore, Emily K., Adam, Kieran, Azoulay-Alfaguter, Inbar, Mor, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664140/
https://www.ncbi.nlm.nih.gov/pubmed/36419471
http://dx.doi.org/10.1016/j.omtm.2022.10.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664140/
https://www.ncbi.nlm.nih.gov/pubmed/36419471
http://dx.doi.org/10.1016/j.omtm.2022.10.012

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