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An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats

Aim: Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy that results in death from right ventricular failure (RVF). There is limited understanding of the molecular mechanisms of RVF in PAH. Methods: In a PAH-RVF model induced by injection of adult male rats with monocrota...

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Detalles Bibliográficos
Autores principales: Hindmarch, Charles Colin Thomas, Tian, Lian, Xiong, Ping Yu, Potus, Francois, Bentley, Rachel Emily Teresa, Al-Qazazi, Ruaa, Prins, Kurt W., Archer, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664166/
https://www.ncbi.nlm.nih.gov/pubmed/36388115
http://dx.doi.org/10.3389/fphys.2022.966454