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An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats
Aim: Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy that results in death from right ventricular failure (RVF). There is limited understanding of the molecular mechanisms of RVF in PAH. Methods: In a PAH-RVF model induced by injection of adult male rats with monocrota...
Autores principales: | Hindmarch, Charles Colin Thomas, Tian, Lian, Xiong, Ping Yu, Potus, Francois, Bentley, Rachel Emily Teresa, Al-Qazazi, Ruaa, Prins, Kurt W., Archer, Stephen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664166/ https://www.ncbi.nlm.nih.gov/pubmed/36388115 http://dx.doi.org/10.3389/fphys.2022.966454 |
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