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Small molecule angiotensin converting enzyme inhibitors: A medicinal chemistry perspective

Angiotensin-converting enzyme (ACE), a zinc metalloprotein, is a central component of the renin–angiotensin system (RAS). It degrades bradykinin and other vasoactive peptides. Angiotensin-converting-enzyme inhibitors (ACE inhibitors, ACEIs) decrease the formation of angiotensin II and increase the l...

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Detalles Bibliográficos
Autores principales: Zheng, Wenyue, Tian, Erkang, Liu, Zhen, Zhou, Changhan, Yang, Pei, Tian, Keyue, Liao, Wen, Li, Juan, Ren, Changyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664202/
https://www.ncbi.nlm.nih.gov/pubmed/36386190
http://dx.doi.org/10.3389/fphar.2022.968104