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Danshensu methyl ester enhances autophagy to attenuate pulmonary fibrosis by targeting lncIAPF–HuR complex

Pulmonary fibrosis is an irreversible fibrotic process that has a high mortality rate and limited treatment options; thus, developing a novel therapeutic drug is critical. In this study, we synthesized danshensu methyl ester (DME) and explored its anti-pulmonary fibrotic ability on TGF-β1-stimulated...

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Detalles Bibliográficos
Autores principales: Zhu, Qi, Wang, Jing, Ji, Yunxia, Luan, Jianlin, Yue, Dayong, Liu, Weili, Li, Hongbo, Zhang, Jinjin, Qu, Guiwu, Lv, Changjun, Song, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664248/
https://www.ncbi.nlm.nih.gov/pubmed/36386240
http://dx.doi.org/10.3389/fphar.2022.1013098