Ancestry, ACKR1 and leucopenia in patients with systemic lupus erythematosus

OBJECTIVE: SLE is more prevalent in populations of African (AA) than European ancestry (EA) and leucopenia is common. A homozygous variant in ACKR1 (rs2814778-CC) is associated with lower white cell counts; the variant is common in AA but not EA populations. We hypothesised that in SLE: (1) leucopen...

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Detalles Bibliográficos
Autores principales: Chung, Cecilia P, Karakoc, Gul, Liu, Ge, Gamboa, Jorge L, Mosley, Jonathan D, Cox, Nancy J, Stein, C Michael, Kawai, Vivian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664301/
https://www.ncbi.nlm.nih.gov/pubmed/36376015
http://dx.doi.org/10.1136/lupus-2022-000790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664301/
https://www.ncbi.nlm.nih.gov/pubmed/36376015
http://dx.doi.org/10.1136/lupus-2022-000790

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