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An iron-deficient diet prevents alcohol- or diethylnitrosamine-induced acute hepatotoxicity in mice by inhibiting ferroptosis

The liver is easily injured by exogenous chemicals through reactive oxygen species (ROS), which lead to ferroptosis, a ROS-dependent programmed cell death characterized by iron accumulation and lipid peroxidation. However, whether iron restriction has a positive role in chemicals-induced liver injur...

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Detalles Bibliográficos
Autores principales: Gao, Zelong, Wang, Dongyao, Zhang, Hongwei, Yang, Jianxin, Li, Min, Lu, Hongtao, Shen, Hui, Tang, Yuxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664348/
https://www.ncbi.nlm.nih.gov/pubmed/36387594
http://dx.doi.org/10.1016/j.crfs.2022.11.001