NKT cells adopt a glutamine-addicted phenotype to regulate their homeostasis and function

Natural killer T (NKT) cells operate distinctly different metabolic programming from CD4 T cells, including a strict requirement for glutamine to regulate cell homeostasis. However, the underlying mechanisms remain unknown. Here, we report that at a steady state, NKT cells have higher glutamine leve...

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Detalles Bibliográficos
Autores principales: Kumar, Ajay, Yarosz, Emily L., Andren, Anthony, Zhang, Li, Lyssiotis, Costas A., Chang, Cheong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664378/
https://www.ncbi.nlm.nih.gov/pubmed/36288696
http://dx.doi.org/10.1016/j.celrep.2022.111516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664378/
https://www.ncbi.nlm.nih.gov/pubmed/36288696
http://dx.doi.org/10.1016/j.celrep.2022.111516

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