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NKT cells adopt a glutamine-addicted phenotype to regulate their homeostasis and function
Natural killer T (NKT) cells operate distinctly different metabolic programming from CD4 T cells, including a strict requirement for glutamine to regulate cell homeostasis. However, the underlying mechanisms remain unknown. Here, we report that at a steady state, NKT cells have higher glutamine leve...
Autores principales: | Kumar, Ajay, Yarosz, Emily L., Andren, Anthony, Zhang, Li, Lyssiotis, Costas A., Chang, Cheong-Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664378/ https://www.ncbi.nlm.nih.gov/pubmed/36288696 http://dx.doi.org/10.1016/j.celrep.2022.111516 |
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