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P-Rex1 Mediates Glucose-Stimulated Rac1 Activation and Insulin Secretion in Pancreatic β-Cells

BACKGROUND/AIMS: Despite the published evidence implicating phosphoinositide 3-kinase (PI3-kinase) in the regulation of islet function, limited information is available on the putative contributory roles of its downstream signaling steps, including the phosphatidylinositol-3,4,5-trisphosphate-depend...

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Detalles Bibliográficos
Autores principales: Thamilselvan, Vijayalakshmi, Gamage, Suhadinie, Harajli, Ali, Chundru, Sri Aneesha, Kowluru, Anjaneyulu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664382/
https://www.ncbi.nlm.nih.gov/pubmed/33347743
http://dx.doi.org/10.33594/000000310