Cargando…

Tick-borne encephalitis virus capsid protein induces translational shutoff as revealed by its structural–biological analysis

Tick-borne encephalitis virus (TBEV) is the most medically relevant tick-transmitted Flavivirus in Eurasia, targeting the host central nervous system and frequently causing severe encephalitis. The primary function of its capsid protein (TBEVC) is to recruit the viral RNA and form a nucleocapsid. Ad...

Descripción completa

Detalles Bibliográficos
Autores principales: Selinger, Martin, Novotný, Radim, Sýs, Jakub, Roby, Justin A., Tykalová, Hana, Ranjani, Ganji Sri, Vancová, Marie, Jaklová, Kateřina, Kaufman, Filip, Bloom, Marshall E., Zdráhal, Zbyněk, Grubhoffer, Libor, Forwood, Jade K., Hrabal, Richard, Rumlová, Michaela, Štěrba, Ján
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664413/
https://www.ncbi.nlm.nih.gov/pubmed/36223838
http://dx.doi.org/10.1016/j.jbc.2022.102585