LGR6-dependent conditional inactivation of E-cadherin and p53 leads to invasive skin and mammary carcinomas in mice

Tissue-specific inactivation of E-cadherin combined with tumor suppressor loss leads to invasive and metastatic cancers in mice. While epidermal E-cadherin loss in mice induces squamous cell carcinomas, inactivation of E-cadherin in the mammary gland leads to invasive lobular carcinoma. To further e...

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Detalles Bibliográficos
Autores principales: ter Steege, Eline J., Sijnesael, Thijmen, Enserink, Lotte, Klarenbeek, Sjoerd, Haakma, Wisse E., Bakker, Elvira R.M., Derksen, Patrick W.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664519/
https://www.ncbi.nlm.nih.gov/pubmed/36371908
http://dx.doi.org/10.1016/j.neo.2022.100844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664519/
https://www.ncbi.nlm.nih.gov/pubmed/36371908
http://dx.doi.org/10.1016/j.neo.2022.100844

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