Tumor cell-derived asymmetric dimethylarginine regulates macrophage functions and polarization

BACKGROUND: Asymmetric dimethylarginine (ADMA), which is significantly elevated in the plasma of cancer patients, is formed via intracellular recycling of methylated proteins and serves as a precursor for resynthesis of arginine. However, the cause of ADMA elevation in cancers and its impact on the...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Ling, Lowery, AKaychia T., Lin, Samuel, Walker, Ameae M., Chen, Kuan-Hui E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664648/
https://www.ncbi.nlm.nih.gov/pubmed/36376929
http://dx.doi.org/10.1186/s12935-022-02769-7