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IL-11 system participates in pulmonary artery remodeling and hypertension in pulmonary fibrosis

BACKGROUND: Pulmonary hypertension (PH) associated to idiopathic pulmonary fibrosis (IPF) portends a poor prognosis. IL-11 has been implicated in fibrotic diseases, but their role on pulmonary vessels is unknown. Here we analyzed the contribution of IL-11 to PH in patients with IPF and the potential...

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Detalles Bibliográficos
Autores principales: Milara, Javier, Roger, Inés, Montero, Paula, Artigues, Enrique, Escrivá, Juan, Cortijo, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9664718/
https://www.ncbi.nlm.nih.gov/pubmed/36376885
http://dx.doi.org/10.1186/s12931-022-02241-0